PUBLICATIONS

LIST BY YEAR: 201720162015  |  2014  |  2013  |  2012  |  2011  |  2010  |  2009  |  2008  |  2007  |  2006  |  2005

**Authors in BOLD denote Klein Lab members

 


2017


  1. Cole JB, Manyama M, Larson JR, Liberton DK, Ferrara TM, Riccardi SL, Li M, Mio W, Klein OD, Santorico SA, Hallgrimsson B, Spritz RA. Human facial shape and size heritability and genetic correlations. Genetics 2017 Feb;205(2):967-78.  Click Here to View
  2. Wald T, Spoutil F, Osickova A, Prochazkova M, Benada O, Kasparek P, Bumba L, Klein OD, Sedlacek R, Sebo P, Prochazka J, Osicka R. Intrinsically disordered proteins drive enamel formation via an evolutionarily conserved self-assembly motif. Proc Natl Acad Sci U S A 2017 Feb;114(9). Click Here to View
  3. Tsai YH, Nattiv R, Dedhia PH, Nagy MS, Chin AM, Thomson M, Klein OD, Spence J. In vitro patterning of pluripotent stem cell-derived intestine recapitulates in vivo human development. Development 2017 Mar;144(6):1045-55. Click Here to View
  4. Niethamer TK, Larson AR, O'Neil AK, Bershteyn M, Hsiao EC, Klein O, Pomerantz JH, Bush JO. EPHRIN-B1 mosaicism drives cell segregation in craniofrontonasal syndrome hiPCS-Derived neuroepithlial cells. Stem Cell Reports 2017 Mar;8(3):529-37. Click Here to View
  5. Kim R, Green JBA, Klein OD. From snapshots to movies: Understanding early tooth development in four dimensions. Dev Dyn 2017 Jun;246(6):442-50. Click Here to View
  6. Hu JK, Du W, Shelton SJ, Oldham MC, DiPersio CM, Klein OD. An FAK-YAP-mTOR Signaling Axis Regulates Stem Cell-Based Tissue Renewal in Mice. Cell Stem Cell 2017 Apr;pii: S1934-5909(17)30094-2. doi: 10.1016/j.stem.2017.03.023. [Epub ahead of print] Click Here to View
  7. Seidel K, Marangoni P, Tang C, Houshmand B, Du W, Maas RL, Murray S, Oldham MC, Klein OD. Resolving stem and progenitor cells in the adult mouse incisor through gene co-expression analysis. Elife 2017 May;6. pii: e24712. doi: 10.7554/eLife.24712. Click Here to View

 


2016


  1. Tapaltsyan V, Charles C, Hu J, Mindell D, Ahituv N, Wilson GM, Black BL, Viriot L, Klein OD. Identification of novel Fgf enhancers and their role in dental evolution. Evol Dev 2016 Jan;18(1):31-40. Click Here to View
  2. Jheon AH, Prochazkova M, Meng B, Wen T, Lim YJ, Naveau A, Espinoza R, Cox TC, Sone ED, Ganss B, Siebel CW, Klein OD. Inhibition of Notch Signaling During Mouse Incisor Renewal Leads to Enamel Defects. J Bone Miner Res 2016 Jan;31(1):152-62. Click Here to View
  3. Rooney GE, Goodwin AF, Depeille P, Sharir A, Schofield CM, Yeh E, Roose JP, Klein OD, Rauen KA, Weiss LA, Ullian EM. Human iPS cell-derived neurons uncover the impact of increased Ras signaling in Costello syndrome. J Neurosci 2016 Jan;36(1):142-52. Click Here to View
  4. Belinson H, Nakatani J, Babineau BA, Birnbaum RY, Ellegood J, Bershteyn M, McEvilly RJ, Long JM, Willert K, Klein OD, Ahituv N, Lerch JP, Rosenfeld MG, Wynshaw-Boris A. Prenatal β-catenin/Brn2/Tbr2 transcriptional cascade regulates adult social and stereotypic behaviors. Mol Psychiatry 2016 Oct;21(10):1417-33.  Click Here to View
  5. Du W, Prochazka J, Prochazkova M, Klein OD. Expression of FGFs during mouse tongue development. Gene Expr Patterns 2016 Mar;20(2):81-7. Click Here to View
  6. Joo A, Long R, Cheng Z, Alexander C, Chang W, Klein OD. Sprouty2 regulates endochondral bone formation by modulation of RTK and BMP signaling. Bone 2016 Jul;88:170-9. Click Here to View
  7. Brinkley JF, Fisher S, Harris MP, Holmes G, Hooper JE, Jabs EW, Jones KL, Kesselman C, Klein OD, Maas RL, Marazita ML, Selleri L, Spritz RA, Van Bakel H, Visel A, Williams TJ, Wysocka J; FaceBase Consortium, Chai Y. The FaceBase Consortium: A comprehensive resource for craniofacial researchers. Development 2016 Jul;143(14):2677-88. Click Here to View
  8. Neben CL, Roberts RR, Dipple KM, Merrill AE, Klein OD. Modeling craniofacial and skeletal congenital birth defects to advance therapies. Hum Mol Genet 2016 Oct;25(R2):R86-R93.  Click Here to View
  9. Belinson H, Savage AK, Fadrosh D, Kuo YM, Lin D, Valladares R, Nusse Y, Wynshaw-Boris A, Lynch SV, Locksley RM, Klein OD. Dual epithelial and immune cell function of Dvl1 regulates gut microbiota composition and intestinal homeostasis. JCI Insight 2016 July;1(10). pii: e85395. Click Here to View
  10. Li C, Hu J, Lu H, Lan J, Du W, Galicia N, Klein OD. aE-catenin inhibits YAP/TAZ activity to regulate signaling centre formation during tooth development. Nature Communications 2016 Jul;7:12133. doi:10.1038/ncomms12133.  Click Here to View
  11. Shaffer JR, Orlova E, Lee MK, Leslie EJ, Raffensperger ZD, Heike CL, Cunningham ML, Hecht JT, Kau CH, Nidey NL, Moreno LM, Wehby GL, Murray JC, Laurie CA, Laurie CC, Cole J, Ferrara T, Santorico S, Klein O, Mio W, Feingold E, Hallgrimsson B, Spritz RA, Marazita ML, Weinberg SM. Genowide-wide association study reveals loci influencing normal human facial morphology. PLoS Genetics 2016 Aug;12(8):e1006149. Click Here to View
  12. Cole JB, Manyama M, Kimwaga E, Mathayo J, Larson JR, Liberton DK, Lukowiak K, Ferrara TM, Riccardi SL, Li M, Mio W, Prochazkova M, Williams T, Li H, Jones KL, Klein OD, Santorico SA, Hallgrimsson B, Spritz RA. Genome-wide association study of facial variation in African children identifies association of SCHIP1 and PDE8A with facial size. PLoS Genetics 2016 Aug;12(8):e1006174. Click Here to View
  13. Sharir A, Klein OD. Watching a deep dive: Live imaging provides lessons about tooth invagination. J Cell Biol 2016 Sep;214(6):645-7.Click Here to View
  14. Koledova Z, Zhang X, Streuli C, Clarke RB, Klein OD, Werb Z, Lu P. SPRY1 regulates mammary epithelial morphogenesis by modulating EGFR-dependent stromal paracrine signaling and ECM remodeling. Proc Natl Acad Sci U S A 2016 Sep;113(39):E5731-40. Click Here to View
  15. Sun Z, Yu W, Sanz Navarro M, Sweat M, Eliason S, Sharp T, Liu H, Seidel K, Zhang L, Moreno M, Lynch T, Holton NE, Rogers L, Neff T, Goodheart MJ, Michon F, Klein OD, Chai Y, Dupuy A, Engelhardt JF, Chen Z, Amendt BA. Sox2 and Lef-1 interact with Pitx2 to regulate incisor development and stem cell renewal. Development 2016 Nov 15;143(22):4115-26. Click Here to View

 


2015


  1. Barlow LA, Klein OD. Developing and regenerating a sense of taste. Curr Top Dev Biol 2015 Jan;111:401-19. Click Here to View
  2. Jheon AH, Prochazkova M, Sherman M, Manoli DS, Shah NM, Carbone L, Klein OD. Spontaneous emergence of overgrown molar teeth in a colony of Prairie voles (Microtus ochrogaster). Int J Oral Sci 2015 Mar;7(1):23-6. Click Here to View
  3. Dye BR, Hill DR, Ferguson MA, Tsai YH, Nagy MS, Dyal R, Wells JM, Mayhew CN, Nattiv R, Klein OD, White ES, Deutsch GH, Spence JR. In vitro generation of human pluripotent stem cell derived lung organoids. Elife 2015 Mar;24:4.Click Here to View
  4. Tian H, Biehs B, Chiu C, Siebel CW, Wu Y, Costa M, de Sauvage FJ, Klein OD. Opposing activities of notch and wnt signaling regulate intestinal stem cells and gut homeostasis. Cell Rep 2015 Apr;11(1):33-42. Click Here to View
  5. Thys A, Vandenberghe P, Hague P, Klein OD, Erneux C, Vanderwinden JM. Hyperplasia of interstitial cells of Cajal in Sprouty homolog 4 deficient mice. PLoS One 2015 Apr;10(4):e0124861. doi: 10.1371/journal.pone.0124861. Click Here to View
  6. Tapaltsyan V, Eronen JT, Lawing AM, Sharir A, Janis C, Jernvall J, Klein OD. Continuously growing rodent molars result from a predictable quantitative evolutionary change over 50 million years. Cell Rep 2015 May;11(5):673-80.  Click Here to View
  7. Zarate YA, Perry H, Ben-Omran T, Sellars EA, Stein Q, Almureikhi M,Simmons K, Klein O, Fish J, Feingold M, Douglas J, Kruer MC, Si Y, Mao R, McKnight D, Gibellini F, Retterer K, Slavotinek A. Further supporting evidence for the SATB2-associated syndrome found through whole exome sequencing. Am J Med Genet A 2015 May;167A(5):1026-32. Click Here to View
  8. Finkbeiner SR, Hill DR, Altheim CH, Dedhia PH, Taylor MJ, Tsai YH, Chin AM, Mahe MM, Watson CL, Freeman JJ, Nattiv R, Thomson M, Klein OD, Shroyer NF, Helmrath MA, Teitelbaum DH, Dempsey PJ, Spence JR. Transcriptome-wide Analysis Reveals Hallmarks of Human Intestine Development and Maturation In Vitro and In Vivo. Stem Cell Reports 2015 Jun;4(6):1140-55. Click Here to View
  9. Marangoni P, Charles C, Tafforeau P, Laugel-Haushalter V, Joo A, Bloch-Zupan A, Klein OD, Viriot L. Phenotypic and evolutionary implications of modulating the ERK-MAPK cascade using the dentition as a model. Sci Rep 2015 Jun;5:11658. doi: 10.1038/srep11658. Click Here to View
  10. Wu D, Mandal S, Choi A, Anderson A, Prochazkova M, Perry H, Gil-Da-Silva-Lopes VL, Lao R, Wan E, Tang PL, Kwok PY, Klein O, Zhuan B, Slavotinek AM. DLX4 is associated with orofacial clefting and abnormal jaw development. Hum Mol Genet 2015 Aug;24(15):4340-52. Click Here to View
  11. Goodwin AF, Kim R, Bush JO, Klein OD. From bench to bedside and back: Improving Diagnosis and treatment of Craniofacial Malformations Utilizing Animal Models. Curr Top Dev Biol 2015 Oct;115:459-92. Click Here to View
  12. Klein OD, Nör JE. Craniofacial stem cells in health and disease. J Dent Res 2015 Nov;94(11)1485-6. Click Here to View
  13. Prochazka J, Prochazkova M, Du W, Spoutil F, Tureckova J, Hoch R, Shimogori T, Sedlacek R, Rubenstein JL, Wittmann T, Klein OD. Migration of founder epithelial cells drives proper molar tooth positioning and morphogenesis. Dev Cell 2015 Dec;35(6):713-24. Click Here to View

 


2014


  1. Li C, Prochazka J, Goodwin A, Klein OD. Fibroblast growth factor signaling in mammalian tooth development. Odontology 2014 Jan;102(1):1-13. Click Here to View
  2. Goodwin A, Tidyman W, Jheon A, Sharir A, Zheng X, Charles C, Fagin J, McMahon M, Diekwisch T, Ganss B, Rauen K, Klein OD. Abnormal Ras signaling in Costello syndrome (CS) negatively regulates enamel formation. Hum Mol Genet 2014 Feb;23(3):682-92. Click Here to View
  3. Kuang-Hsien Hu J, Mushegyan V, Klein OD. On the cutting edge of organ renewal: Identification, regulation, and evolution of incisor stem cells. Genesis 2014 Feb;52(2):79-92. Click Here to View
  4. Ching S, Cunha G, Baskin L, Basson M, Klein OD. Coordinated activity of Spry1 and Spry2 is required fornormal development of the external genitalia. Dev Biol 2014 Feb;386(1):1-11. Click Here to View
  5. Zhao H, Feng J, Seidel K, Shi S, Klein OD, Sharpe P, Chai Y. Secretion of shh by a neurovascular bundle niche supports mesenchymal stem cell homeostasis in the adult mouse incisor. Cell Stem Cell 2014 Feb;14(2):160-73. Click Here to View
  6. Mendelsohn BA, Jeng LL, Oberoi S, Klein OD. Dental findings in 14q terminal deletion syndrome. Clin Dysmorphol 2014 Apr;23(2):60-2. Click Here to View
  7. Chavez MG, Hu J, Seidel K, Li C, Jheon A, Naveau A, Horst O, Klein OD. Isolation and culture of dental epithelial stem cells from the adult mouse incisor. J Vis Exp 2014 May;(87). Click Here to View
  8. Yamada Y, Nakamura S, Klein OD, Ito K. Current trends in stem cell therapy for improvement of bone quality. Histol Histopathol 2014 Jun;29(6):691-7.
  9. Goodwin AF, Oberoi S, Landan M, Charles C, Massie JC, Fairley C, Rauen KA, Klein OD. Craniofacial and dental development in Costello syndrome. Am J Med Genet A 2014 Jun;164A(6):1425-30. Click Here to View
  10. Sun F, Wan M, Xu X, Gao B, Zhou Y, Sun J, Cheng L, Klein OD, Zhou X, Zheng L. Crosstalk between miR-34a and Notch Signaling Promotes Differentiation in Apical Papilla Stem Cells (SCAPs). J Dent Res 2014 Jun;93(6):589-95. Click Here to View
  11. Naveau A, Seidel K, Klein OD. Tooth, hair and claw: comparing epithelial stem cell niches of ectodermal appendages. Exp Cell Res 2014 Jul;325(2):96-103. Click Here to View
  12. Michailovici I, Harrington HA, Azogui HH, Yahalom-Ronen Y, Plotnikov A, Ching S, Stumpf MP, Klein OD, Seger R, Tzahor E. Nuclear to cytoplasmic shuttling of ERK promotes differentiation of muscle stem/progenitor cells. Development 2014 Jul;141(13):2611-20. Click Here to View Commentary on our paper in Science Signalling - Click Here to View
  13. Castillo D, Seidel K, Salcedo E, Ahn C, de Sauvage FJ, Klein OD, Barlow LA. Induction of ectopic taste buds by SHH reveals the competency and plasticity of adult lingual epithelium. Development 2014 Aug;141:2993-3002. Click Here to View
  14. Harjunmaa E, Seidel K, Häkkinen T, Renvoisé E, Corfe IJ, Kallonen A, Zhang ZQ, Evans AR, Mikkola ML, Salazar-Ciudad I, Klein OD, Jernvall J. Replaying evolutionary transitions from the dental fossil record. Nature 2014 Aug;512(7512):44-8. Click Here to View Commentary on our paper in Nature - Click Here to View
  15. Goodwin AF, Larson JR, Jones KB, Liberton DK, Landan M, Wang Z, Boekelheide A, Langham M, Mushegyan V, Oberoi S, Brao R, Wen T, Johnson R, Huttner K, Grange DK, Spritz RA, Hallgrímsson B, Jheon AH, Klein OD. Craniofacial morphometric analysis of individuals with X-linked hypohidrotic ectodermal dysplasia. Mol Genet Genomic Med 2014 Sep;2(5):422-9. Click Here to View
  16. Mues G, Bond J, Xiang L, Vieira AR, Seymen F, Klein O, D'Souza RN. The WNT10A gene in ectodermal dysplasias and selective tooth agenesis. Am J Med Genet A 2014 Oct;164A(10):2455-60. Click Here to View

 


2013


  1. Plaks V, Brenot A, Lawson DA, Linnemann JR, Van Kappel EC, Wong KC, de Sauvage F, Klein OD, Werb Z. Lgr5-expressing cells are sufficient and necessary for postnatal mammary gland organogenesis. Cell Rep 2013 Jan;3(1):70-8. Click Here to View
  2. Chavez MG,Yu W, Biehs B, Harada H, Snead ML, Lee JS, Desai TA, Klein OD. Characterization of dental epithelial stem cells from the mouse incisor with two-dimensional and three-dimensional platforms. Tissue Eng Part C Methods 2013 Jan;19(1):15-24. Click Here to View
  3. Griffin JN, Compagnucci C, Hu D, Fish J, Klein O, Marcucio R, Depew MJ. Fgf8 dosage determines midfacial integration and polarity within the nasal and optic capsules. Dev Biol 2013 Feb;374(1):185-97. Click Here to View
  4. Yamada Y, Nakamura S, Ito K, Umemura E, Hara K, Nagasaka T, Abe A, Baba S, Furuichi Y, Izumi Y, Klein OD, Wakabayashi T. Injectable bone tissue engineering using expanded mesenchymal stem cells. Stem Cells 2013 Mar;31(3):572-80. Click Here to View Cover of Stem Cells - Click Here to View
  5. Jheon AH, Seidel K, Biehs B, Klein OD. From molecules to mastication: the development and evolution of teeth. Wiley Interdiscip Rev Dev Biol 2013 Mar-Apr;2(2):165-82. Click Here to View
  6. Juuri E, Jussila M, Seidel K, Holmes S, Wu P, Richman J, Heikinheimo K, Chuong CM, Arnold K, Hochedlinger K, Klein O, Michon F, Thesleff I. Sox2 marks epithelial competence to generate teeth in mammals and reptiles. Development 2013 Apr;140(7):1424-32. Click Here to View
  7. Nusse YM, Klein OD. If a stem cell dies in the crypt, and no one is around to see it.. Cell Stem Cell 2013 Apr;12(4):389-90. Click Here to View
  8. Goodwin AF, Oberoi S, Landan M, Charles C, Groth J, Martinez A, Fairley C, Weiss LA, Tidyman WE, Klein OD, Rauen KA. Craniofacial and dental development in cardio-facio-cutaneous syndrome: the importance of Ras signaling homeostasis. Clin Genet 2013 Jun;83(6):539-44. Click Here to View
  9. Felfly H, Klein OD. Sprouty genes regulate proliferation and survival of human embryonic stem cells. Sci Rep 2013 Jul;3:2277.doi: 10.1038/srep02277. Click Here to View
  10. Biehs B, Hu JK, Strauli NB, Sangiorgi E, Jung H, Heber RP, Ho S, Goodwin AF, Dasen JS, Capecchi MR, Klein OD. BMI1 represses Ink4a/Arf and Hox genes to regulate stem cells in the rodent incisor. Nat Cell Biol 2013 Jul;15(7):846-52. Click Here to View
  11. Lagronova-Churava S, Spoutil F, Vojtechova S, Lesot H, Peterka M, Klein OD, Peterkova R. The dynamics of supernumerary tooth development are differentially regulated by sprouty genes. J Exp Zool B Mol Dev Evol 2013 Jul;320(5):307-20. Click Here to View
  12. Jones KB, Goodwin AF, Landan M, Seidel K, Tran DK, Hogue J, Chavez M, Fete M, Yu W, Hussein T, Johnson R, Huttner K, Jheon AH, Klein OD. Characterization of X-linked hypohidrotic ectodermal dysplasia (XL-HED) hair and sweat gland phenotypes using phototrichogram analysis and live confocal imaging. Am J Med Genet A 2013 Jul;161A(7):1585-93. Click Here to View
  13. Cao H, Jheon A, Li X, Sun Z, Wang J, Florez S, Zhang Z, McManus M, Klein OD, Brad BA. The Pitx2:miR-200c/141:noggin pathway regulates Bmp signaling and ameloblast differentiation. Development 2013 Aug;140(16):3348-59. Click Here to View
  14. Jones KB, Klein OD. Oral epithelial stem cells in tissue maintenance and disease: the first steps in a long journey. Int J Oral Sci 2013 Sep;5(3):121-9. Click Here to View
  15. Oishi PE, Klein OD, Keller RL; University of California San Francisco Neonatology and Pediatric Critical Care Early Faculty Development Committee. Developing physician-scientists in the fields of neonatology and pediatric critical care medicine: an effort to formulate a departmental policy. J Pediatr 2013 Sep;163(3):616-7. Click Here to View
  16. Zheng L, Warotayanont R, Stahl J, Kunimatsu R, Klein OD, Denbesten PK, Zhang Y. Inductive ability of human developing and differentiated dental mesenchyme. Cells Tissues Organs 2013 Oct;198(2):99-110. Click Here to View
  17. Klein OD, Oberoi S, Huysseune A, Hovorakova M, Peterka M, Peterkova R. Developmental disorders of the dentition: An update. Am J Med Genet C Semin Med Genet 2013 Nov;163C(4):318-32. Click Here to View
  18. Klein OD, Bush JO, Knox SM, Jheon AH, Cordero DR, Richtsmeier JT. American Journal of Medical Genetics Part A. The society of craniofacial genetics and developmental biology 35th annual meeting 2013 Dec;161(12):2938-52. Click Here to View

 


2012


  1. Collaborative cross consortium. The genome architecture of the Collaborative Cross mouse genetic reference population. Genetics 2012 Feb;190(2):389-401. Click Here to View Cover of Genetics - Click Here to View
  2. Purcell P, Jheon A, Vivero MP, Rahimi H, Joo A, Klein OD. Spry1 and spry2 are essential for development of the temporomandibular joint. J Dent Res 2012 Apr;91(4):387-93. Click Here to View
  3. Kyrylkova K, Kyryachenko S, Biehs B, Klein O, Kioussi C, Leid M. BCL11B regulates epithelial proliferation and asymmetric development of the mouse mandibular incisor. PLoS One 2012 May;7(5):e37670. doi: 10.1371/journal.pone.0037670. Click Here to View
  4. Li CY, Cha W, Luder HU, Charles RP, McMahon M, Mitsiadis TA, Klein OD. E-cadherin regulates the behavior and fate of epithelial stem cells and their progeny in the mouse incisor. Dev Biol 2012 Jun;366(2):357-66. Click Here to View
  5. Horst OV, Chavez MG, Jheon AH, Desai T, Klein OD. Stem cell and biomaterials research in dental tissue engineering and regeneration. Dent Clin North Am 2012 Jul;56(3):495-520. Click Here to View
  6. Juuri E, Saito K, Ahtiainen L, Seidel K, Tummers M, Hochedlinger K, Klein OD, Thesleff I, Michon F. Sox2+ stem cells contribute to all epithelial lineages of the tooth via Sfrp5+ progenitors. Dev Cell 2012 Aug;23(2):317–28. Click Here to View
  7. Wan M, Gao B, Sun F, Tang Y, Ye L, Fan Y, Klein OD, Zhou X, Zheng L. microRNA miR-34a regulates cytodifferentiation and targets multi-signaling pathways in human dental papilla cells. PLoS One 2012 Nov;7(11): e50090. doi: 10.1371/journal.pone.0050090.  Click Here to View
  8. Justice C, Yagnik G, Kim Y, Peter Y, Jabs W, Erazo M, Ye X, Ainehsazan E, Shi L, Cunningham ML, Kimonis V, Roscioli T, Wall SA, Wilkie AO, Stoler J, Richtsmeierc JT, Heuzé Y, Sanchez-Lara P, Buckley MF, Drusche CF, Mills J, Caggana M, Romitti PA, Kay DM, Senders C, Taub PJ, Klein OD, Boggan J, Zwienenberg-Lee M, Naydenov C, Kim J, Wilson AF, Boyadjiev SA. A genome-wide association study identifies susceptibility loci for nonsyndromic sagittal craniosynostosis near BMP2 and within BBS9. Nature Genetics 2012 Dec;44(12):1360-4. Click Here to View

 


2011


  1. Milunsky JM, Maher TM, Zhao G, Wang Z, Mulliken JB, Chitayat D, Clemens M, Stalker HJ, Bauer M, Burch M, Chénier S, Cunningham ML, Drack AV, Janssens S, Karlea A, Klatt R, Kini U, Klein O, Lachmeijer AM, Megarbane A, Mendelsohn NJ, Meschino WS, Mortier GR, Parkash S, Ray CR, Roberts A, Roberts A, Reardon W, Schnur RE, Smith R, Splitt M, Tezcan K, Whiteford ML, Wong DA, Zori R, Lin AE. Genotype-phenotype analysis of the branchio-oculo-facial syndrome. Am J Med Genet A 2011 Jan;155A(1):22-32. Click Here to View
  2. Jheon AH, Mostowfi P, Snead ML, Ihrie RA, Sone E, Pramparo T, Attardi LD, Klein OD. PERP regulates enamel formation via effects on cell–cell adhesion and gene expression. J Cell Sci 2011 Mar;124(Pt5):745-54. Click Here to View
  3. Petersen CI, Jheon AH, Mostowfi P, Charles C, Ching S, Thirumangalathu S, Barlow LA, Klein OD. FGF signaling regulates the number of posterior taste papillae by controlling progenitor field size. PLoS Genetics 2011 Jun;7(6):e1002098. doi: 10.1371/journal.pgen.1002098. Click Here to View
  4. Hovorakova M, Prochazka J, Lesot H, Smrckova L, Churava S, Boran T, Kozmik Z, Klein O, Peterkova R, Peterka M. Shh expression in a rudimentary tooth offers new insights into development of the mouse incisor. J Exp Zoolog B Mol Dev Evol 2011 Jul;316(5):347-58. Click Here to View
  5. Hochheiser H, Aronow BJ, Artinger K, Beaty TH, Brinkley JF, Chai Y, Clouthier D, Cunningham ML, Dixon M, Donahue LR, Fraser SE, Hallgrimsson B, Iwata J, Klein O, Marazita ML, Murray JC, Murray S, de Villena FP, Postlethwait J, Potter S, Shapiro L, Spritz R, Visel A, Weinberg SM, Trainor PA. The FaceBase Consortium: a comprehensive program to facilitate craniofacial research. Dev Biol 2011 Jul;355(2):175-82. Click Here to View
  6. Charles C, Hovorakova M, Ahn Y, Lyons DB, Marangoni P, Churava S, Biehs B, Jheon A, Lesot H, Balooch G, Krumlauf R, Viriot L, Peterkova R, Klein OD. Regulation of tooth number by fine-tuning levels of receptor-tyrosine kinase signaling. Development 2011 Sep;138(18):4063-73. Click Here to View
  7. Jheon AH, Li CY, Wen T, Michon F, Klein OD. Expression of microRNAs in the stem cell niche of the adult mouse incisor. PLoS One 2011 Sep;6(9):e24536. doi: 10.1371/journal.pone.0024536. Click Here to View
  8. Tian H, Biehs B, Warming S, Leong KG, Rangell L, Klein OD, de Sauvage FJ. A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable. Nature 2011 Sep;478(7368):255-9. Click Here to View Commentary on our paper in Nature Reviews - Click Here to View

 


2010


  1. Kettunen P, Kivimäe S, Keshari P, Klein OD, Cheyette BN, Luukko K. Dact1-3 mRNAs exhibit distinct expression domains during tooth development. Gene Expr Patterns 2010;10:140-3. Click Here to View
  2. Prochazka J, Pantalacci S, Rothova M, Churava S, Lambert A, Lesot H, Klein O, Peterka M, Laudet V, Peterkova R. Patterning by heritage: rudimentary tooth buds shape mouse molar row development. Proc Natl Acad Sci U S A 2010;107:15497-502. Click Here to View
  3. Jelin A, Perry H, Hogue J, Oberoi S, Cotter PD, Klein OD. Clefting in trisomy 9p patients: genotype-phenotype correlation using microarray comparative genomic hybridization. J Craniofac Surg 2010 Sep;21(5):1376-1379. Click Here to View
  4. Ahn Y, Sanderson BW, Klein OD, Krumlauf R. Inhibition of Wnt signaling by Wise/Sostdc1 and negative feedback from Shh controls tooth number and patterning. Development 2010 Oct;137(19):3221-31. Click Here to View
  5. Parsa S, Kuremoto K, Seidel K, Tabatabai R, MacKenzie B, Yamaza T, Akiyama K, Branch J, Koh CJ, Al Alam D, Klein OD, Bellusci S. Signaling by FGFR2b controls the regenerative capacity of adult mouse incisors. Development 2010 Nov;137(22):3743-52. Click Here to View
  6. Seidel K, Ahn CP, Lyons D, Nee A, Ting K, Brownell I, Cao T, Carano RAD, Curran T, Schober M, Fuchs E, Joyner A, Martin GR, de Sauvage FJ, Klein OD. Hedgehog signaling regulates the generation of ameloblast progenitors in the continuously growing mouse incisor. Development 2010 Nov;137(22):3753-61. Click Here to View

 


2009


  1. Caton J, Luder H-U, Zoupa M, Bradman M, Bluteau G, Tucker AS, Klein O, Mitsiadis TA. Enamel-free teeth: Tbx1 deletion affects amelogenesis in rodent incisors. Dev Biol 2009 Apr;328(2):493-505. Click Here to View
  2. Peterkova R, Churava S, Lesot H, Rothova M, Prochazka J, Peterka M, Klein OD. Revitalization of a diastemal tooth primordium in Spry2 null mice results from increased proliferation and decreased apoptosis. J Exp Zoolog B Mol Dev Evol 2009 Jun;312B(4):292-308. Click Here to View
  3. Boran T, Peterkova R, Lesot H, Lyons DB, Peterka M, Klein OD. Temporal analysis of ectopic enamel production in incisors from Sprouty mutant mice. J Exp Zoolog B Mol Dev Evol 2009 Jul;312B(5):473-85. Click Here to View
  4. Charles C, Lazzari V, Tafforeau P, Schimmang T, Tekin M, Klein O, Viriot, L. Modulation of Fgf3 dosage in mouse and men mirrors evolution of mammalian dentition. Proc Natl Acad Sci U S A 2009 Dec;106(52):22364-8. Click Here to View Commentary on our paper in Nature - Click Here to View

 


2008


  1. Klein OD, Lyons DB, Balooch G, Marshall GW, Basson MA, Peterka M, Boran T, Peterkova R, Martin GR. An FGF signaling loop sustains the generation of differentiated progeny from stem cells in mouse incisors. Development 2008 Jan;135(2):377-85. Click Here to View Summary of our paper in Development - Click Here to View
  2. Metzger RJ, Klein OD, Martin GR, Krasnow MA. The branching programme of mouse lung development. Nature 2008 Jun;453(7196):745-50. Click Here to View Commentary on our paper in Nature - Click Here to View
  3. Klein OD, Kostiner DR, Weisiger K, Moffatt E, Lindeman N, Goodman S, Tuchman M, Packman S. Acute fatal presentation of ornithine transcarbamylase deficiency in a previously healthy male. Hepatol Int 2008 Sep;2(3):390–4. Click Here to View
  4. Kalfa N, Liu B, Klein O, Audran F, Wang MH, Cao M, Sultan C, Baskin L. Mutations of cxorf6 are associated with a range of severities of hypospadias. Eur J Endocrinol 2008 Oct;159(4):453-8. Click Here to View
  5. Kalfa N, Liu B, Klein O, Wang MH, Cao M, Baskin L. Genomic variants of atf3 in patients with hypospadias. J Urol 2008 Nov;180(5):2183-8. Click Here to View

 


2007


  1. Klein OD, Cotter PD, Moore MW, Zanko A, Gilats M, Epstein CJ, Conte F, Rauen KA. Interstitial deletions of chromosome 6q: genotype-phenotype correlation utilizing array CGH. Clin Genet 2007 Mar;71(3):260–6. Click Here to View
  2. D'Souza RD and Klein OD. Unraveling the molecular mechanisms that lead to supernumerary teeth in mice and men: current concepts and novel approaches. Cells, Tissues, Organs 2007 Jul;186(1):60–9 Click Here to View

 


2006


  1. Klein OD, Minowada G, Peterkova R, Kangas A, Yu BD, Lesot H, Peterka M, Jernvall J, Martin GR. Sprouty genes control tooth number via bidirectional antagonism of epithelial-mesenchymal FGF signaling. Dev Cell 2006 Aug;11(2):181-90. Click Here to View
  2. Enns G, Cowan T, Klein O, Packman S. Aminoacidopathies and organic acidemias. In: Swaiman K, Ashwal S, Ferriero D, eds. Pediatric Neurology: Principles and Practice. Philadelphia: Elsevier, 2006.

 


2005 and earlier


  1. Klein OD, Backstrand K, Cotter PD, Marco E, Sherr E, Slavotinek A. Case report: Y;6 translocation with deletion of 6p. Clin Dysmorphol 2005 Apr;14(2):93-6. Click Here to View
  2. Ahn CP, Lachman RS, Cox VA, Blumberg B, Klein OD. Brachydactylic multiple delta phalanges plus syndrome. Am J Med Genet A 2005 Sep;138(1):41-4. Click Here to View
  3. Klein OD, Cotter PD, Schmidt AM, Bick DP, Tidyman WE, Albertson DG, Pinkel D, Rauen KA. Interstitial deletion of chromosome 12q: Genotype-phenotype correlation of two patients utilizing array comparative genomic hybridization. Am J Med Genet A 2005 Nov;138(4):349-54. Click Here to View
  4. Klein OD, Cotter PD, Albertson DG, Pinkel D, Tidyman WE, Moore MW, Rauen KA. Prader-Willi syndrome resulting from an unbalanced translocation: characterization by array comparative genomic hybridization. Clin Genet 2004 Jun;65(6):477-82. Click Here to View
  5. Klein O, Kegler-Ebo D, Su J, Smith S, DiMaio D. The bovine papillomavirus E5 protein requires a juxtamembrane negative charge for activation of the platelet-derived growth factor beta receptor and transformation of C127 cells. J Virol 1999 Apr;73(4):3264-72 Click Here to View
  6. Raga F, Bonilla-Musoles F, Casañ EM, Klein O, Bonilla F. Assessment of endometrial volume by three-dimensional ultrasound prior to embryo transfer: clues to endometrial receptivity. Hum Reprod 1999 Nov;14(11):2851-4.Click Here to View
  7. DiMaio D, Lai CC, Klein O. Virocrine transformation: the intersection between viral transforming proteins and cellular signal transduction pathways. Annu Rev Microbiol 1998 Oct; 52:397-421. Click Here to View
  8. Klein O, Polack GW, Surti T, Kegler-Ebo D, Smith SO, DiMaio D. Role of glutamine 17 of the bovine papillomavirus E5 protein in platelet-derived growth factor beta receptor activation and cell transformation. J Virol 1998 Nov;72(11):8921-32. Click Here to View
  9. Surti T, Klein O, Aschheim K, DiMaio D, Smith SO. Structural models of the bovine papillomavirus E5 protein. Proteins 1998 Dec;33(4):601-12. Click Here to View
  10. Lee ME, Dyer DH, Klein OD, Bolduc JM, Stoddard BL, Koshland DE, Jr. Mutational analysis of the catalytic residues lysine 230 and tyrosine 160 in the NADP(+)-dependent isocitrate dehydrogenase from Escherichia coli. Biochemistry 1995 Jan;34(1):378-84. Click Here to View